Difference between heartwood and sapwood
Forest Products Laboratory (U.S.)
1919
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Relatório de estágio de mestrado em Ensino do 1.º e 2.º Ciclo do Ensino Básico
Reactivation of telomerase has been implicated in human tumorigenesis, but the underlying mechanisms remain poorly understood. Here we report the presence of recurrent somatic mutations in the TERT promoter in cancers of the central nervous system (43%), bladder (59%), thyroid (follicular cell-derived, 10%) and skin (melanoma, 29%). In thyroid cancers, the presence of TERT promoter mutations (when occurring together with BRAF mutations) is significantly associated with higher TERT mRNA expression, and in glioblastoma we find a trend for increased telomerase expression in cases harbouring TERT promoter mutations. Both in thyroid cancers and glioblastoma, TERT promoter mutations are significantly associated with older age of the patients. Our results show that TERT promoter mutations are relatively frequent in specific types of human can...
Fundação para a Ciência e a Tecnologia (FCT)
Olga Martinho is recipient of a PhD fellowship (SFRH/BD/36463/2007) from Fundação para a Ciência e Tecnologia (FCT), Portugal.
In the most developed States colorblindness affects 10% of the male population. This handicap incurs limitations as well as uncomfortable personal and social situations for those afflicted that depend on others to choose products in which color is a predominant factor, such as pieces of apparel and decoration. A sample group of colorblind people showed in a recent study found relevant the development of a system which would allow them to identify colors. The development of a graphic color identification system was the answer to this need, its concept and structure make it universal, easy to communicate and memorize. This system can be used in a variety of products and allow the colorblind to reduce or even eliminate their dependence on others.
We have witnessed a change in the Health Information Systems (HIS) in what concerns structure, contents and support aiming an optimization of the resources, the best efficiency in cost control and a better management of the quality of services rendered to the citizens.
From the standpoint of reformulating the HIS, we can see an evolution in the production of information centered almost exclusively in the need of a documental proof on the care rendered by nurses to the citizens to produce information that can constitute a central resource for their clinical decision making.
We aim to describe the evolution of the Nursing Information Systems (NIS), reflect upon the impact of reformulation and implementation of the NIS in Portugal in the development of the nursing practice and reflect upon the impact of the NIS reformulation in the qua...
Relatório de estágio de mestrado em Ensino do 1º e 2º Ciclo do Ensino Básico
